Avandia Side Effects

Avandia side effects include 43% greater risk of heart attack or heart failure

If you have severe heart failure (very poor pumping ability of the heart), you cannot be started on Avandia. Avandia is also not recommended if you have heart failure with symptoms (such as shortness of breath or swelling) even if these symptoms are not severe.

Avandia side effects include:

  • Heart Failure – Avandia can cause your body to keep extra fluid (fluid retention), which leads to swelling and weight gain. Extra body fluid can make some heart problems worse or lead to heart failure.
  • Swelling (edema) from fluid retention – Call your doctor right away if you have symptoms such as:
    • swelling or fluid retention, especially in the ankles or legs
    • shortness of breath or trouble breathing, especially when you lie down
    • an unusually fast increase in weight
    • unusual tiredness
  • Heart Problems – Avandia may increase the risk of heart problems related to reduced blood flow to the heart. These include possible increases in the risk of angina (heart-related chest pain) or myocardial infarction (“heart attack”). This risk appeared higher in patients who took Avandia with insulin or with nitrate medication. The use of Avandia with insulin or nitrate medication is not recommended. If you have chest pain, or a feeling of chest pressure, seek immediate medical attention.
  • Low blood sugar (hypoglycemia) – Lightheadedness, dizziness, shakiness or hunger may mean that your blood sugar is too low. This can happen if you skip meals, if you use another medicine that lowers blood sugar, or if you have certain medical problems. Call your doctor if low blood sugar levels are a problem for you.
  • Fractures – usually in the hand, upper arm or foot, in females. Talk to your doctor for advice on how to keep your bones healthy.
  • Weight Gain – Avandia can cause weight gain that may be due to fluid retention or extra body fat. Weight gain can be a serious problem for people with certain conditions including heart problems. Call your doctor if you have an unusually fast increase in weight.
  • Anemia – Low red blood cell count.
  • Ovulation leading to pregnancy – Ovulation may happen in premenopausal women who do not have regular monthly periods. This can increase the chance of pregnancy.
  • Liver Problems – It is important for your liver to be working normally when you take Avandia. Your doctor should do blood tests to check your liver before you start taking Avandia and during treatment as needed. Call your doctor right away if you have unexplained symptoms such as:
    • nausea or vomiting
    • stomach pain
    • unusual or unexplained tiredness
    • loss of appetite
    • dark urine
    • yellowing of your skin or the whites of your eyes

The most common side effects of Avandia included cold-like symptoms, injury, and headache.


Patient information

Avandia can cause or worsen heart failure.

Avandia may increase your risk of other heart problems that occur when there is reduced blood flow to the heart, such as chest pain (angina) orheart attack (myocardial infarction). This risk appeared higher in patients taking medicines called nitrates or insulin. Taking Avandia with insulin or with nitrates is not recommended.

If you have chest pain or a feeling of chest pressure, you should seek immediate medical attention, regardless of what diabetes medicines you are taking.

If you take Avandia, tell your doctor right away if you:

  • Have swollen legs or ankles, a rapid increase in weight or difficulty breathing, or unusual tiredness
  • Experience changes in vision
  • Become pregnant

Review your medical history and tell your doctor if you:

  • Have heart failure or other heart problems
  • Have liver problems or liver disease
  • Are pregnant or are nursing

Women taking Avandia should know that Avandia may increase the risk of pregnancy.

More fractures have been observed in women taking Avandia.


Free legal consultation

If you or a loved one have suffered serious side effects while takingAvandia, if you have been diagnosed with blood clots, heart attack, orstroke, or if you are experiencing the symptoms associated with any of these serious side effects, you may have a claim against the manufacturer of Avandia.

Please contact us today by filling out the brief questionnaire, or by calling our toll free number (1-800-898-2034) for a free, no-cost no-obligation evaluation of your case.